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Lu-Min Wang

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Open access Jul 2026

Exosome-mediated hepatocellular carcinoma progression by modulating macrophage metabolic reprogramming and macrophage M2 polarization via exosome-derived hsa_circ_0057320-miR-28-5p/E2F6 axis.

Exosomes derived from HOXD3-treated HCCs induced macrophage polarization toward the M2 phenotype via metabolic reprogramming, and exosomes derived from HOXD3-induced HCC cells promotes M2 macrophage polarization via metabolic reprogramming, thereby accelerating HCC malignancy.

Lu-Min Wang, Chenyang Qiao, Zhiqiang Wang et al. · 1 citation

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