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Author

Luran Wang

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#machine learning Preprint Sep 2026

Specificity-Aware Diffusion Steering via Variance-Reduced Sequential Monte Carlo

Inference-time steering enables pretrained diffusion models to satisfy new constraints without full retraining. However, specificity-aware generation is difficult: repelling samples from a negative reference distribution can also erode the positive distribution where the two overlap. The key challenge is to suppress ne...

Lu-Ran Wang, Lin-Rui Ma, Hannes Stärk et al. · 0 citations
Jul 2026

Site-directed mutagenesis of α-L-rhamnosidase boosts its deglycosylation activity for the production of bioactive flavonoid glycosides.

The rational engineering of an α-L-rhamnosidase (DthRha) to address limitations and enhance its performance for flavonoid production highlights the R783A mutant as a robust and thermally stable biocatalyst with great potential for the sustainable production of bioactive flavonoids.

Haoyu Jia, Luran Wang, Tong Yan et al. · 1 citation

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