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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

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Lu-Xin Wei

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Review Open access Sep 2026

Advancing In Vivo Chimeric Antigen Receptor T‐Cell Engineering to Accelerate Clinical Translation

ABSTRACT Chimeric antigen receptor T‐cell (CAR‐T) therapy is a transformative tumor immunotherapy that redirects autologous T cells to eliminate malignant cells. However, its broader clinical translation is constrained by complex and costly ex vivo manufacturing, variable product quality, and limited control over in vi...

Zhen-Xin Bai, Ming Yi, Sheng-Tao Hu et al. · 0 citations

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