Author

Luyan Z. Ma

2 papers indexed here

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Open access Aug 2026

Structural insights into a substrate translocation pathway revealed by the RND efflux pump complex MexJK from Pseudomonas aeruginosa

Resistance–nodulation–cell division (RND) efflux pumps are the major cause of multidrug resistance in Pseudomonas aeruginosa. The inner membrane protein MexK from P. aeruginosa is a narrow-spectrum RND transporter. It assembles with membrane fusion protein MexJ and outer membrane proteins to form a tripartite efflux co...

Zhikun Wu, Ziyue Meng, Wei Huang et al. · Science Advances · 0 citations

Open access Aug 2026

F‐Type Pyocin Versus Phage λ Tail: Conserved Hub, Divergent Fibers

The structural basis of F‐type pyocin assembly and host recognition is defined, conserved and unique features relative to phage λ are revealed, and a framework for engineering tailocins as precision antimicrobials against drug‐resistant P. aeruginosa is provided.

Zhiwei Gu, Yu-Fan Xie, Lan-Xin Wang et al. · Advancement of science · 0 citations