Review
Sep 2026
Bacterial metabolic-immune reprogramming in cancer: from living vectors to engineered biofactories.
Tumor immunotherapy has transformed modern oncology, yet its clinical efficacy against solid tumors remains severely restricted by complex physiological and immunosuppressive barriers. Distinct from passive delivery systems, live bacteria can actively navigate into hypoxic tumor cores and intrinsically modulate local i...
Jun-Jie Wu, Li-Shang Xu, Qi-Wen Chen et al.
· Journal of Controlled Releas... · 0 citations