Open access
Jul 2026
Capabilities, specificity gaps and training-data dependence of AlphaFold3 across diverse application areas
It is found that, while AF3 can perform well in favourable settings, this performance is uneven across applications and its predictions and use of confidence metrics will depend strongly on the specific application area and must be interpreted with respect to training-set overlap.
O. Follonier, Yan Liu, Pablo Campomanes et al.
· bioRxiv · 1 citation