Developmentally-regulated post-apocrine cell death of Drosophila salivary glands utilizes ER stress-linked apoptosis
It is shown that SG apoptosis is linked to endoplasmic reticulum (ER) disintegration via an ER-stress mechanism, and genetic manipulation of ER-resident proteins, chaperones and co-chaperones resulted in a widespread and fast vesiculation of the ER, typical of that seen during the final apoptotic stage in wild type ani...