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Lucie Rudl Kulhavá

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Open access Aug 2026

Using Hydrogen/Deuterium Exchange in Untargeted LC-MS Analysis of Small Molecules

Liquid chromatography–hydrogen/deuterium exchange–mass spectrometry (LC-HDX-MS) provides orthogonal structural information that complements conventional LC-MS and improves confidence in small-molecule structural elucidation. Although HDX-MS is well established in protein research, its application to small molecules rem...

Tomáš Čajka, J. Hricko, Lucie Rudl Kulhavá et al. · 0 citations

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