Open access
Sep 2026
Scalable expansion of human iNKT cells: single-cell profiling and in vivo control of GvHD with preserved GvL activity
A scalable culture system to preferentially expand human CD4− iNKT cells directly from total peripheral blood mononuclear cells (PBMCs) using alpha-galactosylceramide (α-GalCer) and optimized cytokine conditions and IL-15 was the most effective cytokine.
Jordan Brouard, Cristina Caraiman, Ghislain Fievet et al.
· bioRxiv · 0 citations