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Author

Lucio Giuseppe Granata

3 papers indexed here

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Review Sep 2026

[Artificial intelligence in cardiovascular prevention: a strategic opportunity for risk prediction and early diagnosis].

Overall, AI outlines the transition from a reactive cardiology model toward a predictive, proactive, and precision-based approach in cardiovascular prevention, with a specific focus on risk stratification, early detection of subclinical disease, and identification of patients most likely to benefit from targeted interventions.

Simona Giubilato, L. Granata, S. Petrina · 0 citations
Review Open access Aug 2026

Zilebesiran, a Small Interfering RNA Therapeutic Targeting Angiotensinogen: Mechanism, Clinical Evidence, Safety, and Implementation Considerations

Zilebesiran is a first-in-class, subcutaneously administered small interfering RNA therapeutic that selectively silences angiotensinogen messenger RNA, the transcript encoding the common precursor of all angiotensin peptides and produces durable blood pressure lowering that can persist for up to 6 months after a single dose.

Jawaria, A. Noor, Yusra Zarlashat et al. · 0 citations
Review Open access Aug 2026

Lipoprotein(a) in cardiovascular disease: pathophysiology, residual risk, and emerging therapeutic strategies

This narrative review summarizes the molecular biology, genetics, epidemiology, pathophysiological mechanisms, and clinical relevance of Lp(a), and critically examines current and emerging therapeutic strategies aimed at reducing Lp(a)-mediated cardiovascular risk.

L. Granata, Simona Giubilato, Francesca Campanella et al. · 0 citations

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