Open access
Aug 2026
Longitudinal 1H NMR metabolomics of serum in a chronic temporal lobe epilepsy model reveals systemic metabolic remodeling
The convergence of the metabolic profiles of drug-sensitive and drug-resistant animals suggests that the systemic effects of chronic epilepsy and phenobarbital treatment dominate the serum metabolome, potentially masking subtle molecular signatures associated with drug resistance.
Veronica Ghini, Lucrezia Cosottini, M. Scordino et al.
· Frontiers in Molecular Biosc... · 0 citations