Lucy C. Walters

Innate immune imprints shape HIV-1 reservoir cell persistence during long-term antiretroviral therapy

Host immune responses that can target and eliminate HIV-1 reservoir cells during suppressive antiretroviral therapy are poorly understood. Here, analyzing over 6,000 proviral DNA amplicons from 104 individuals on long-term antiretroviral therapy, we found that carriers of HLA-C2 allotypes, which promote NK cell educati...