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Author

Luis Felipe Espinal Pérez

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Review Open access Sep 2026

Cutaneous-Ocular Manifestations in Systemic Inflammatory Diseases: Clinical Patterns, Early Recognition, and Multidisciplinary Management

Systemic inflammatory diseases may simultaneously affect the skin and ocular structures, generating clinical patterns that can contribute to earlier recognition of underlying immune-mediated disorders. This review analyzed the relationship between cutaneous and ocular manifestations in systemic lupus erythematosus, Sjö...

Ana Patricia Torres Barrios, Sandra Carolina Méndez Sosa, Luis Felipe Espinal Pérez et al. · 0 citations
Review Open access Sep 2026

Patient-Centered Facial and Orofacial Reconstruction After Cutaneous Cancer Resection: Integrating Function, Aesthetics, and Quality of Life

Facial and orofacial reconstruction following cutaneous oncologic resection represents a complex clinical challenge in which tumor control must be integrated with preservation of function, restoration of facial appearance, and maintenance of quality of life. This study analyzed contemporary reconstructive strategies us...

Sandro José Nava Daza, Erick Fernando Flores García, Luis Felipe Espinal Pérez et al. · 0 citations
Review Open access Sep 2026

Immunometabolic Dysregulation and Cognitive Dysfunction in Major Depressive Disorder: The Role of Chronic Low-Grade Inflammation

Major depressive disorder is a heterogeneous psychiatric condition frequently accompanied by persistent cognitive dysfunction involving executive function, attention, memory, processing speed, and motivational processes. Increasing evidence suggests that chronic low-grade inflammation and immunometabolic dysregulation...

Juan José Parra Serpa, Catalina Antonia de Jesús, Anabel Stephanny Ortiz Dávila et al. · 0 citations
Review Open access Aug 2026

Early Neuropsychiatric and Cutaneous Manifestations as Sentinel Signs of Systemic Disease

The reviewed evidence showed that systemic lupus erythematosus presented the broadest clinical heterogeneity, while neurological manifestations in Sjögren syndrome may precede classical glandular symptoms.

Jocelyne Keren Hinojosa Villanueva, Luis Felipe Espinal Pérez, Juan José Parra Serpa et al. · 0 citations
Review Open access Jul 2026

Biological Skin Rejuvenation in the Regenerative Era: Clinical Applications of Exosomes and Polynucleotides in Modern Dermatology

The available evidence demonstrates encouraging results in facial rejuvenation, photoaging, scar remodeling, chronic wound healing, periocular rejuvenation, and hair restoration, with improvements in skin quality and high patient satisfaction while maintaining a favorable short-term safety profile.

Fabio Camilo Jaramillo Contreras, A. Clemente, M. Martínez et al. · 0 citations

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