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Sponsored AI Networking Cookbook: Practical recipes for AI-assisted network automation and development AI Networking Cookbook: Practical recipes for AI-assisted network automation and development

Author

Luisa F. Escobar-Hoyos

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Sep 2026

Abstract A024: A plastic, MYC -dependent KRT17 +/ GATA6 + hybrid state drives chemoresistance and therapeutic vulnerability in pancreatic cancer

Pancreatic ductal adenocarcinoma (PDAC) progression is driven by cellular heterogeneity not fully captured by the classical (GATA6+) versus basal-like (KRT17+) model. Intermediary states are linked to aggression, but their characteristics remain unclear. Here, we deconstruct this heterogeneity using a KRT17/GATA6 fra...

Lyanne A. Delgado-Coka, Andrew E. Resnick, Jonathan D. Ogata et al. · 0 citations
Sep 2026

Abstract B050: ERK1 splicing switch triggers lethal hyperactivation and overcomes KRAS inhibitor resistance in pancreatic cancer

Pancreatic ductal adenocarcinoma (PDAC) is projected to become the second leading cause of cancer death in the United States by 2040. Oncogenic KRAS, present in ∼90% of PDACs, drives tumor growth through MAPK signaling and ERK1/2 activation. While pan-RAS and mutant-selective KRAS inhibitors can produce initial r...

Luisa F. Escobar-Hoyos, Md Siraj Afjalus, Deanne E. Yugawa et al. · 0 citations

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