Author

Lujia Liu

2 papers indexed here

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Open access Aug 2026

Quercetin protects HTR-8/SVneo human trophoblast cells against oxidative stress injury via activating EGFR/PI3K/AKT-NRF2/HO-1 signaling axis

Adverse pregnancy outcomes represented by recurrent spontaneous abortion remain a global clinical problem, with excessive oxidative stress-induced trophoblast dysfunction as its well-recognized core pathological mechanism. Quercetin is a natural flavonoid with strong antioxidant and cytoprotective effects, but its prot...

Lu-Jia Liu, Zhixian Ding, Yina Wu et al. · Frontiers in Pharmacology · 0 citations

Review Open access Aug 2026

Iron regulation by Sirtuins 1 & 2 and their therapeutic modulation by Sirtinol

Sirtuins 1 & 2 (SIRTs 1 & 2) are deacetylases that are overexpressed in several types of cancer, thereby contributing to various hallmarks of cancer, such as increased proliferation and chemoresistance. Therefore, these enzymes represent potential therapeutic targets. Sirtinol is a small-molecule pharmacological inhibi...

Koffi Amegble, Lu-Jia Liu, To-Ni Q. Duan et al. · Frontiers in Pharmacology · 0 citations