Abstract Pain modulation is a fundamental survival mechanism that prioritises, shapes, and suppresses nociceptive inputs to optimise behaviour. Although acute pain signals potential or actual tissue damage, sustained pain can impair essential behaviours, necessitating modulatory circuits that dynamically regulate nocic...
Luke A. Henderson, L. Crawford, James W. M. Kang et al.· Pain· 0 citations
This study provides the first evidence of subregional hypothalamic activation in CRPS in response to noxious stimulation, and indicates altered autonomic circuits may contribute to ongoing pain in CRPS, identifying them as therapeutic targets for this debilitating chronic pain condition.
Yun-Li Huang, M. Russo, P. D. Drummond et al.· Journal of Pain· 0 citations
Brain imaging studies have identified structural alterations in individuals with chronic neuropathic pain, particularly in regions involved in sensory, emotional, and cognitive processing. However, most studies remain cross-sectional, leaving the temporal progression of these changes during pain chronification unclear....
Angela Doshen, L. Crawford, James W. M. Kang et al.· Journal of Neuroscience· 0 citations
We use cookies to run the site and, with your consent, for analytics and to show ads.
See our Cookie Policy.