Open access
Oct 2026
N6 ‐Methyladenosine Demethylase FTO Protects Pancreatic ΒTC6 Cells From Cholesterol‐Triggered Damage by Regulating Nfatc4: Insights From RNA‐Seq Analysis
ABSTRACT Excessive cholesterol contributes to pancreatic β‐cell dysfunction and plays a critical role in the pathogenesis of metabolic disorders. FTO is a well‐characterized N6‐methyladenosine (m6A) demethylase involved in the regulation of RNA metabolism; however, its role in pancreatic β‐cells under cholesterol‐induc...
Ping-Ping Hong, Yong-Jie Li, Jian-Dong Lin et al.
· Chemical Biology and Drug De... · 0 citations