Jul 2026
Ubiquitin-specific protease 11 promotes tubular cell senescence via inhibiting p53 ubiquitin degradation during renal fibrosis.
It is demonstrated that the KLF4-USP11-p53 axis drives tubular senescence and renal fibrosis, representing a highly promising therapeutic target for CKD.
Xin Wang, Ming Ning, Heng-Min Wang et al.
· Cellular Signalling · 0 citations