Open access
Aug 2026
Scalable Production of Transfection-Grade Plasmid DNA by Liquid–Liquid Extraction Without Chromatography: Application to CAR-T Vector Packaging
The acidic phenol extraction method is a robust, scalable, and cost-effective alternative to industry-standard methods, matching them in yield and purity while being readily scalable, making it a practical tool for both academic research and preparative laboratory production.
Gaziza Nigmatulla, Aitolkyn Kydyrbayeva, T. Kulatay et al.
· Bioengineering · 0 citations