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Lyle A. Simmons

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Review Open access Jul 2026

Ribonucleotide errors, RNase HII, and ribonucleotide excision repair

Replicative DNA polymerases are responsible for the high-fidelity duplication of genomes in all organisms. The overall DNA replication process is highly accurate, with deoxyribonucleoside monophosphate (dNMP) errors occurring on the order of 1 in tens of millions of replicated bases. However, DNA polymerases are more p...

Julianna R. Cresti, Lyle A. Simmons · 0 citations

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