Open access
Jul 2026
Association between the PNPLA3 I148M (rs738409) polymorphism and risk of metabolic dysfunction-associated steatotic liver disease: a meta-analysis (2015-2025).
This updated meta-analysis confirms that the PNPLA3 rs738409 (I148M) polymorphism is a major genetic susceptibility factor for MASLD across diverse populations and supports the incorporation of PNPLA3 into multifactorial risk assessment models.
Muteia'a Hamood, M. A. Al-Salehi, A. Hussein et al.
· BMC Gastroenterology · 0 citations