Author

M. A. López-Luis

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Open access Aug 2026

TagR, a newly identified member of the MarR family of transcriptional regulators, represses the NRPS operon in Klebsiella oxytoca

ABSTRACT Toxigenic Klebsiella oxytoca strains produce the pyrrolobenzodiazepine enterotoxins tilimycin (TM) and tilivalline (TV), which contribute to the development of antibiotic-associated hemorrhagic colitis. The biosynthesis of these toxins depends on the nonribosomal peptide synthetase (NRPS) operon located within...

Cristopher Perez, M. A. López-Luis, Carlos J Jiménez-Sánchez et al. · Microbiology spectrum · 0 citations

Review Open access Aug 2026

Computational Genomics for Resistome Characterization: Current Advancements and Future Challenges Under a One Health Perspective

The resistome, defined as the complete set of antibiotic resistance genes (ARGs) present in the microbiota of a given environment, is a critical component for understanding the evolutionary dynamics of antimicrobial resistance (AMR) and its impact on human, animal, and environmental health. This review summarizes curre...

Lenin García Gutiérrez, A. Méndez-Tenorio, M. A. López-Luis et al. · Antibiotics · 0 citations