M. Adamzik

Development and evaluation of machine learning-based prediction-modelling for initial vancomycin serum concentrations in septic ICU patients using clinical health record data

Sepsis remains a life-threatening condition with highly heterogeneous and dynamic pathophysiology, limiting the effectiveness of uniform therapeutic strategies. Beyond timely source control, antimicrobial therapy represents the only causal treatment option. Vancomycin is widely used for treatment of Gram-positive infec...