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Author

M. Ang

h-index 13 View on Semantic Scholar

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Review Sep 2026

Structural evolution of ionizable lipids for nucleic acid delivery

This Review provides insights into the challenges and gaps for translation, manufacturing and expansion of lipid nanoparticle-mediated nucleic acid therapeutics for precision RNA medicine while highlighting next-generation principles and translational perspectives that may guide precision RNA therapeutics in regenerati...

Lu-Lu Xue, M. Ang, K. Swingle et al. · 0 citations
Review 2026

Transient T cell therapies.

The pharmacological imperative for transient CAR expression is delineated, including lipid nanoparticles in combination with mRNA, which avoids risks of insertional mutagenesis and enables titratable, short-lived CAR expression, thereby enhancing safety management and suitability for applications beyond oncology.

Yudian Xiao, Ming-Liang Bai, M. Ang et al. · 0 citations

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