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Author

M. Argun

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Open access Aug 2026

The Venom of Tarantula Cubensis (Theranekron) Reduces Apoptosis and Mitochondrial Oxidative Toxicity Caused by NaIO3–Induced Age-Related Macular Degeneration in Human Retinal Pigment Epithelium Cells

Excessive generations of apoptosis and oxygen free radicals (OFRs) are two main common reasons of age-related macular degeneration (AMD). A homeopathic preparation of the Tarantula Cubensis spider venom is Theranekron (TNE). The antiapoptotic and antioxidant actions of TNE were indicated in different disease models exc...

M. Argun, Ö. Çelik · 0 citations
Open access Sep 2026

Resveratrol mitigates hypoxia-induced mitochondrial oxidative damage and apoptosis via inhibition of TRPA1 channel in retinal pigment epithelial cells.

HBO exposure through TRPA1-mediated Ca2+ signaling, induces mitochondrial oxidative cell cytotoxicity and death, which may offer a treatment option for HPO-induced retinal disorders linked to increased OFR and Ca2+ influx.

M. Argun, Mustafa Nazıroğlu · 0 citations

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