M. Ashafaq

Design, synthesis, and preliminary anticancer evaluation of diphenylpropan-1-one derivatives: in vitro, in vivo and in silico studies

Breast cancer is a leading cause of cancer-associated mortality and morbidity worldwide, and there is a continued need for structurally diverse anticancer agents with improved properties. The present study reports a series of diphenylpropan-1-one (DPP) derivatives (4a–4i), rationally designed around a chalcone framewor...