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Sponsored Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt

Author

M. Beckstead

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3 papers indexed here

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Open access Oct 2026

A new epigenetic framework for DNA methylation, hydroxymethylation, and gene expression during brain aging

DNA modifications are epigenetic marks added directly to DNA bases that can stably or dynamically regulate gene expression, allowing cells to maintain their identity while also having flexibility to adapt to changes in their environment1. Aging is often thought to disrupt this regulation, causing cells to lose their id...

Sarah R. Ocañas, Walker Hoolehan, Kevin Pham et al. · 0 citations
Open access Sep 2026

PFKFB2 Gates a Relationship Between Cardiac Glycolytic Regulation and Electrophysiological Function

BACKGROUND: The cardiac isoform of phosphofructokinase-2/fructose 2,6-biphosphatase (PFKFB2) is the heart’s strongest glycolytic regulator but is degraded in the absence of insulin signaling. This makes PFKFB2 loss critical to understand in metabolic heart disease, of which impaired insulin signaling is a hallmark. Pro...

Kylene M. Harold, Harris E. Blankenship, Keaton E. Minor et al. · 0 citations
Feb 2026

Pathogenic tau in the mouse locus coeruleus produces noradrenergic hyperactivity and neuropsychiatric phenotypes reminiscent of early Alzheimer’s disease

It is demonstrated that pTau triggers phenotypes reflective of LC-NE hyperactivity in the early stages of AD pathogenesis, laying the foundation for the development of LC-based disease-modifying therapies to address neuropsychiatric manifestations.

Anuradha Korukonda, Harris E. Blankenship, K. Kam et al. · 3 citations

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