Both extracts showed antimicrobial activity and selective cytotoxicity against HepG2 cells, with minimal toxicity toward normal WI-38 fibroblasts, and stable interactions of major phenolics with the Bcl-2 protein were confirmed, confirming the importance of tissue-specific evaluation of mushroom extracts.
Salma O. Jadallah, Yassmin F. El Greeby, Mohammed Alakib et al.· Bulletin of the Chemical Soc...· 0 citations
This study investigated Altissimacoumarin H (ATSC), a naturally occurring terpenylated coumarin, using an integrated in silico workflow combining target prediction, network pharmacology, transcriptomic assessment, molecular docking, molecular dynamics, ADME/toxicity prediction, and density functional theory (DFT).
S. Bufarwa, M. Belaidi· Journal of Computational Bio...· 0 citations
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