Comparative diagnostic challenges in two horses with skin fragility disorders
Hereditary equine regional dermal asthenia (HERDA) is an autosomal recessive connective tissue disorder of horses caused by a missense mutation (c.115G>A) in the peptidyl‐prolyl cis–trans isomerase B ( PPIB ) gene, resulting in defective collagen organisation. Clinically and histopathologically, HERDA may resembl...