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Author

M. Bolognesi

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Review Open access Oct 2026

Recent advances of GPR40 agonists as potential anti-Alzheimer's agents.

Alzheimer's disease (AD) is a progressive and multifactorial neurodegenerative disorder involving metabolic dysfunction, neuroinflammation, mitochondrial impairment, synaptic failure, and neuronal loss. Although amyloid-beta deposition and neurofibrillary tangles composed of hyperphosphorylated tau remain central patho...

Jefferson Muniz Alves da Silva, A. Kümmerle, D. A. Rodrigues et al. · 0 citations
Review Open access Aug 2026

Targeting IGF2BP3 in Cancer: From Molecular Structure and Biology to Early Drug Discovery

This review describes the structural organization of IGF2BP3, the molecular basis of RNA recognition, and the mechanisms underlying its dysregulation across human cancers and discusses emerging therapeutic approaches, including direct inhibition of IGF2BP3–RNA interactions and indirect strategies that rewire IGF2BP3 ex...

Elisa Uliassi, M. Bolognesi, K. Scotlandi et al. · 0 citations

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