Author

M. Bos

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Open access Aug 2026

Pseudonaja textilis venom factor Va circumvents natural regulatory mechanisms via a unique A2 domain region.

The ptFV A2T represents an exceptional structural element driving the enhanced procoagulant functions that are at the basis of the snake venom's extreme toxicity.

Mark Schreuder, K. Cheung, Lynn Kruijsdijk et al. · Journal of Thrombosis and Ha... · 0 citations

Open access Aug 2026

Substitution-induced allosteric activation of coagulation factor IX as a potential alternative hemophilia A treatment strategy.

Targeted modification of regions surrounding the FIXa active site enables allosteric activation, providing a potential foundation for novel bypassing strategies in hemophilia A therapy.

Viola J. F. Strijbis, K. Cheung, D. Gobbo et al. · Thrombosis Research · 0 citations