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M. C. Nguyen

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Open access Sep 2026

Perseus: lineage-aware refinement of Kraken2 taxonomic classification for long read metagenomes

Perseus is presented, a lineage-aware confidence estimation framework for taxonomic classification that models the spatial distribution and hierarchical consistency of k-mer evidence along sequences that consistently and substantially reduces the false assignment rate while improving precision and lineage-consistent ac...

M. C. Nguyen, Michael C. Schatz · 0 citations

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