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Author

M. Castanho

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Open access Sep 2026

Insights into the mechanism of action of the bipartite fusion module of SARS-CoV-2 spike protein

ABSTRACT SARS-CoV-2 entry into host cells is mediated by the spike glycoprotein, which promotes fusion between viral and host membranes. Despite its importance, the precise location and mode of action of the fusion peptide, a key spike region that inserts into and perturbs the host membrane, remain elusive. Two regions...

Carolina C. Buga, Mariana Valério, M. Alenquer et al. · 0 citations
Open access Aug 2026

Comparative characterization of six teleost piscidins reveals distinct antimicrobial, antibiofilm and stability profiles.

It is demonstrated that integrating structural prediction with experimental validation is an effective strategy for identifying fish-derived innate immune peptides as candidates for biomedical applications.

Patricia Asensio-Calavia, Sergio González-Acosta, M. Cavaco et al. · 0 citations

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