Abstract Background Externalizing disorders encompass a range of disinhibited behaviors that typically manifest in youth and are linked with adverse psychological and social outcomes. Polygenic liability to externalizing behaviors has been associated with psychiatric and disease phenotypes in adults. Identifying correl...
S. Paul, Nathaniel S. Thomas, M. Choi et al.· Psychological Medicine· 0 citations
Importance: Preventing substance use disorder (SUD) is a top public health priority, but clinical practice currently lacks validated prognostic tools to identify risk before the onset of heavy use/problems. Objective: To determine whether models can predict SUD using genetic, behavioral, and environmental factors and t...
I-Tzu Hung, F. Aliev, I.-C. S. Kuo et al.· medRxiv· 0 citations
Among individuals with AUD, high EXT PGS was associated with CD/ASPD, arousal/aggression alcohol expectancies, and relaxation/tension reduction alcohol expectancies; high MDD PGS was associated with MDD and neuroticism.
G. Dash, F. Aliev, S. Kuo et al.· Alcohol, clinical & experime...· 0 citations
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