Author

Min‐Koo Choi

2 papers indexed here

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Open access Sep 2026

Enhanced Dissolution and Oral Bioavailability of Tegoprazan Using D-α-Tocopheryl Polyethylene Glycol 1000 Succinate-Based Melt Granulation System

Tegoprazan (TPZ) is a promising potassium-competitive acid blocker, but its pH-dependent low solubility often leads to erratic oral absorption. Although several hydrophilic polymer-based amorphous solid dispersions have been attempted to enhance dissolution, they often suffer from thermodynamic instability or rely on c...

M. Jeong, Tae Hyoung Kim, I. Yang et al. · Molecules · 0 citations

Aug 2026

Ready-to-use, spheronized drug particles-embedded iron(III)-reinforced carboxymethyl cellulose hydrogels as novel long-acting injectable platform with reduced local inflammation.

This study aimed to construct a ready-to-use, spheronized drug particle-embedded iron(III)-reinforced carboxymethyl cellulose hydrogel (Fe3+-CMC HG) as a novel long-acting injectable (LAI) platform for hydrophobic drugs. Dutasteride (DTS), a lipophilic 5α-reductase inhibitor prescribed for benign prostatic hyperplasia,...

Min Young Jeong, D. Shin, I. Yang et al. · International journal of pha... · 0 citations