Author

M. Colella

2 papers indexed here

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Review Open access Sep 2026

Mitochondrial dysfunction as a metabolic checkpoint of immunotherapy response in colorectal cancer

Immunotherapy has markedly improved outcomes across multiple cancer types; however, colorectal cancer (CRC) remains largely refractory, with meaningful responses mostly restricted to tumors harboring deficient mismatch repair and high microsatellite instability (dMMR/MSI-H), which represent only a small fraction of CRC...

Lorenzo Tomassini, M. Colella, G. Monteleone et al. · Frontiers in Immunology · 0 citations

Open access Aug 2026

BRD4 contributes to the cytokine-induced acquisition of an IL-13RA2-positive inflammatory fibroblast phenotype

BRD4 contributes to cytokine-induced inflammatory activation and pro-inflammatory functions of intestinal fibroblasts in IBD, and may represent a potential strategy to modulate stromal cell-driven inflammation.

R. Frascatani, M. Serra, Andrea Iannucci et al. · Journal of Crohn's & Colitis · 0 citations