Open access
Jul 2026
Spatial tissue analysis of secondary sarcoma following CAR T cell therapy for B cell lymphoma
The prevalence of CAR-positive T cells in patient-derived tissue sections, observed metabolic and proliferative shifts in the tumor and its microenvironment, and immune checkpoint analysis provide insights into post-CAR T secondary cancers and highlight tools that may guide future targeted therapies.
Jia-Jye Lee, Peirong Hu, Kun Luo et al.
· iScience · 0 citations