Errors in linear registration can propagate to downstream nonlinear registration and bias volumetric estimations, deformation-based morphometry (DBM) and voxel-based morphometry (VBM) analyses. Subtle linear registration errors are particularly challenging as they are difficult to detect and may not result in obvious f...
Zhao-Jin Chen, R. Moqadam, A. Metz et al.· bioRxiv· 0 citations
Introduction Myelin water imaging provides a non-invasive approach for indirectly investigating myelin content of the brain by magnetic resonance Imaging (MRI). Myelin water fraction (MWF) reflects the fraction of water signal associated with water trapped between myelin layers. Postmortem imaging provides a unique opp...
L. Sanches, Narges Taghizadehsalehabad, R. Moqadam et al.· bioRxiv· 0 citations
INTRODUCTION: Cognitively stimulating activity (CSA) is associated with cognitive health, but whether associations with cognitive change differ by life stage and sex remains unclear. METHODS: Data were drawn from Rush cohorts. Participants were 2,614 adults aged 65 years and older (1,965 females; 649 males). CSA during...
S. Goulding, S. Raeesi, J. A. Anderson et al.· medRxiv· 0 citations
These findings, replicated in four diverse and independent datasets, support imaging-based subtyping as a scalable and clinically translatable approach for capturing heterogeneity in AD pathophysiology and associated cognitive trajectories.
A. Metz, Cassandra Polizzi, R. Moqadam et al.· medRxiv· 0 citations
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