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Open access Sep 2026

Population-scale immune multiome atlas reveals regulatory disease mechanisms.

Most disease-associated genetic variants lie in non-coding regions1,2, yet mechanistic insights are limited by the lack of an empirical framework for characterizing the molecular consequences of regulatory variation. Single-cell molecular quantitative trait locus (QTL) mapping3,4 connects variants to gene regulation bu...

Masahiro Kanai, T. Delorey, Jarno Honkanen et al. · 2 citations
Open access Sep 2026

Contribution of copy number variants to schizophrenia in East Asian populations

A significantly elevated genome-wide rare CNV burden in EAS cases compared with controls is observed, underscoring the importance of increasing population diversity to fully capture the genetic underpinnings of schizophrenia.

Yu Chen, Qi-Di Feng, Max Lam et al. · 0 citations

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