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Author

M. de Brot

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2 papers indexed here

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Open access Oct 2026

Hereditary Breast Cancer in a Brazilian Referral Cohort: Germline Diversity and Genotype–Phenotype Associations

The germline landscape of hereditary breast cancer has been characterized predominantly in populations of European ancestry, with limited evidence from populations with different demographic histories. We investigated germline diversity and genotype–phenotype associations in a single-center ambispective cohort at a ter...

A. Cicilini, P. Batista, S. Caputo et al. · 0 citations
Open access Nov 2026

BRCA1 and HRR pathway genes in triple-negative breast cancer patients: clinical outcomes in an admixed Brazilian cohort

Triple-negative breast cancer (TNBC) is an aggressive and heterogeneous subtype of breast cancer, frequently associated with early-onset disease, hereditary susceptibility and African ancestry. A substantial proportion of TNBC cases are linked to germline pathogenic variants (gPVs) in BRCA1 , a key gene in th...

R. Brianese, K. Santiago, Gabriel Bandeira Do Carmo et al. · 0 citations

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