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Open access Oct 2026

Incremental prognostic value of late gadolinium enhancement in hypertrophic cardiomyopathy in a large contemporary cohort

Late gadolinium enhancement (LGE) on cardiac magnetic resonance (CMR) reflects myocardial fibrosis and has been associated with adverse outcomes in hypertrophic cardiomyopathy (HCM). We sought to measure its incremental prognostic value beyond established clinical and phenotypic variables in a large contemporary HCM...

H. Sheashaa, S. Keen, S. Shah et al. · 0 citations
Open access Oct 2026

Incremental prognostic value of extracellular volume fraction in hypertrophic cardiomyopathy in a large contemporary cohort

Left ventricular (LV) myocardial extracellular volume (ECV), derived from cardiac magnetic resonance (CMR) T1 mapping, reflects diffuse interstitial fibrosis and has emerged as a quantitative marker of adverse myocardial remodeling in hypertrophic cardiomyopathy (HCM). We aimed to determine the independent prognostic...

S. Shah, S. Keen, H. Sheashaa et al. · 0 citations
Open access Oct 2026

Long-term outcomes of hypertrophic cardiomyopathy patients undergoing septal reduction therapies: Results from the NHLBI HCMR registry

Current methods to predict risk of adverse events in hypertrophic cardiomyopathy (HCM) are based on retrospective studies from select tertiary centers. The HCM Registry (HCMR) is a prospective registry, funded by the NHLBI, USA to aid in development of clinical and imaging markers that could improve event predict...

M. Desai, P. Kolm, J. Di Marco et al. · 0 citations

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