Open access
Sep 2026
HSPA1A transcriptionally activated by HSF1 facilitates mitophagy via inducing PINK1 phosphorylation to suppress mitochondrial apoptosis in hyperplastic prostate
Benign prostatic hyperplasia (BPH) is a highly prevalent, age-related disorder in men, defined by nonmalignant enlargement of the prostate, which results in bothersome lower urinary tract symptoms and impaired quality of life. Heat shock protein family A member 1 A (HSPA1A)/HSP70, as a molecular chaperone, plays a cr...
Huan Liu, Ji-Zhang Qiu, Huan Lai et al.
· Cell Death & Disease · 0 citations