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M. El-Zahed

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Open access Sep 2026

Novel Azo Sulfonamide Derivatives of 5-Sulfosalicylic Acid: Synthesis, Biological Evaluation, and Computational Profiling

The escalating crisis of multi-drug-resistant pathogens necessitates the development of novel therapeutic scaffolds with enhanced membrane permeability and multi-target inhibitory potential. This study describes the design, synthesis, and mechanistic evaluation of five novel azo-sulfonamide hybrids (4a–e) derived from...

Samar H. Ali, M. El-Zahed, Elham Negm et al. · 0 citations
Sep 2026

Chitosan–Antipyrine Schiff Base Nanocomposites With ZnO or Ag Nanoparticles: Synthesis, Characterization, and Dye Adsorption With Preliminary Biological Assessment

A novel chitosan Schiff base derivative (CSB) was synthesized by chemically modifying chitosan with antipyrine. This modified matrix was subsequently used to prepare nanocomposites through the encapsulation of zinc oxide (CSB/ZnO) and silver (CSB/Ag) nanoparticles. Fourier‐transform infrared spectroscopy (FTIR), x‐...

A. Elsayed, H. H. Abdel-Razik, F. Eltaweel et al. · 0 citations
Open access Aug 2026

Synthesis, structural elucidation, antimicrobial performance, and DNA-binding behavior of a new N2O2 tetradentate schiff base and its transition metal and uranyl complexes

A new tetradentate N2O2 Schiff base ligand derived from 2,6-diaminopyridine and 2,4-dihydroxybenzaldehyde was synthesized and used to prepare its Cu(II), Co(II), Ni(II), Mn(II), and UO2 (II) complexes. The ligand and complexes were fully characterized by elemental analysis, FT-IR, UV–Vis, 1H/13C NMR, ESR, mass spectrom...

Reham H. Wahba, M. A. Diab, E. A. Gomaa et al. · 0 citations

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