Author

M. Empting

2 papers indexed here

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Review Open access Sep 2026

Phenazine Biosynthesis Inhibitors as Pseudomonas aeruginosa Antivirulence Agents

Phenazines are redox-active secondary metabolites produced by a variety of bacteria, including Pseudomonas aeruginosa, a Gram-negative opportunistic pathogen associated with severe, often chronic infections and particularly notorious for its multiple resistance mechanisms. A major contributor to P. aeruginosa virulen...

Maria Handke, Janosch Baumgarten, Marie Thiemann et al. · ACS Bio & Med Chem Au · 0 citations

Open access Aug 2026

Tracheal tuft cell-released leukotrienes promote antibacterial immune responses.

Tuft cells (TCs) act as crucial airway sentinels that detect bacterial metabolites and initiate immune responses, yet the underlying mechanisms remain poorly understood. Here, we identify tracheal TCs as the initial source of leukotrienes (LTs), released during bacterial infection. Tracheal TCs discriminate pathogenic...

M. I. Elhawy, N. A. Wadood, Maria Grammer et al. · Cell Reports · 0 citations