Open access
Aug 2026
FAM136A is an essential chaperone for mitochondrial membrane protein biogenesis
It is concluded that FAM136A is an IMS-resident chaperone, necessary and sufficient to maintain nascent membrane proteins in a folding-competent state to mediate their integration into the bilayer.
M. Ernst, Jichen Zhang, Haoqi Xu et al.
· bioRxiv · 0 citations