M. F. Coronel

Kainate-induced ATP release contributes to spinal excitotoxicity that is attenuated by purinergic blockade.

Introduction Severe spinal cord injury (SCI) is characterized by irreversible neuronal loss and permanent motor/sensory dysfunction with very limited treatment. This study aimed to assess the role of purinergic signalling at a very early stage of SCI following focal chemical injury induced by kainate (KA). Methods Ma...