Open access
Sep 2026
Myogenic dysregulation underlies human tongue overgrowth in Beckwith-Wiedemann syndrome
Summary Macroglossia is a clinically significant feature of Beckwith-Wiedemann syndrome (BWS), but the cellular basis of tongue overgrowth remains poorly defined. Using pediatric tongue specimens from molecularly defined BWS subtypes and age-matched nonBWS controls, we show that BWS macroglossia is characterized by ske...
Elisia D. Tichy, Anna T. Nguyen, Mariah Byrne et al.
· iScience · 0 citations