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Open access Sep 2026

Reconstructing host-pathogen interactions: analysis of the intercellular network of macrophages and other immune cells within an aspergillosis-on-chip model

Abstract The human-pathogenic fungus Aspergillus fumigatus can cause life-threatening infections, particularly in immunosuppressed or neutropenic patients with hematological malignancies. The human antifungal immune response primarily relies on neutrophils with contribution from macrophages, while the roles of unconven...

Simranpreet Kaur, A. K. Renner, Pauline Porschitz et al. · 0 citations
Open access Aug 2026

Functional analysis of Candida albicans protein kinases identifies Crk1 as a modulator of epithelial cell damage

A phenotypic pattern of medium- and epithelial cell type-specific cytotoxicity displayed by a C. albicans protein kinase mutant suggests that Crk1 regulates processes linked to carbon and amino acid metabolism that are relevant to interactions with intestinal epithelial cells.

A. Möslinger, Allon Weiner, S. Schäuble et al. · 1 citation

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