Author

M. G. Finn

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Open access Aug 2026

Immunization with the Tc85-Derived Peptide Displayed on Virus-like Particles Confers Protection against Trypanosoma cruzi Infection

Chagas disease, caused by the Trypanosoma cruzi, remains a major global health burden with limited prophylactic options. We describe a vaccine platform that leverages a peptide epitope derived from the T. cruzi trans-sialidase group II (Tc85pep), displayed on the virus-like particle derived from the PP7 bacteriophage,...

Ugochukwu Oduwe, Giorgi Kenkebashvili, Syed Uddin et al. · ACS Omega · 0 citations

Open access Dec 2010

Repeated administration of the GABAB receptor positive modulator BHF177 decreased nicotine self-administration, and acute administration decreased cue-induced reinstatement of nicotine seeking in rats

Results showed that BHF177 selectively blocked nicotine self-administration and prevented cue-induced reinstatement of nicotine seeking, with minimal effects on responding for food and no effect on cue-induced reinstatement of food seeking, which could be useful therapeutics for the treatment of different aspects of ni...

S. Vlachou, S. Guéry, Wolfgang Froestl et al. · Psychopharmacology · 770 citations · ⚡47