M. G. Larimi

Polymorphic structures of rapidly twisting 40-residue amyloid-β fibrils

Cryogenic electron microscopy is used to characterize the structure of rapidly twisting Aβ40 fibrils, for which the distance between apparent width minima in electron microscope images (“cross-over distances”) is approximately 25 nm, and contributes to the understanding of amyloid polymorphism, connections between morp...